Expresión de búsqueda: GLUTAREDOXINS 
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Descriptor Inglés:   Glutaredoxins 
Descriptor Español:   Glutarredoxinas 
Descriptor Portugués:   Glutarredoxinas 
Sinónimos Inglés:   Glutaredoxin  
Categoría:   D08.811.682.667.084
Definición Inglés:   A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE. 
Nota Histórica Inglés:   2008(1980); use PROTEINS 1979 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   52721 
Identificador Único:   D054477 

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