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STAT5 TRANSCRIPTION FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
STAT5 Transcription Factor
Descriptor
Spanish
:
Factor de Transcripción STAT5
Descriptor
Portuguese
:
Fator de Transcrição STAT5
Tree Number:
D12.644.360.024.342.500
D12.776.157.057.186.500
D12.776.476.024.421.500
D12.776.930.840.500
Definition
English
:
A signal transducer and activator of transcription that mediates cellular responses to a variety of
CYTOKINES
. Stat5 activation is associated with transcription of
CELL CYCLE
regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic
genes
such as BCL-2
GENES
. Stat5 is constitutively activated in many
patients
with acute MYELOID
LEUKEMIA.
History Note
English
:
2006(1992)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50798
Unique Identifier:
D050799
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS