Search on: GLUTAMATE-CYSTEINE LIGASE 
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Descriptor English:   Glutamate-Cysteine Ligase 
Descriptor Spanish:   Glutamato-Cisteína Ligasa 
Descriptor Portuguese:   Glutamato-Cisteína Ligase 
Synonyms English:   gamma-Glutamyl-Cysteine Synthetase  
Tree Number:   D08.811.464.259.850.400
Definition English:   One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of gamma-glutamylcysteine from glutamate and cysteine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.2. 
History Note English:   98(77) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   5860 
Unique Identifier:   D005721 

Occurrence in VHL:
 

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