Search on:
ERYTHROMYCIN ESTOLATE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Erythromycin Estolate
Descriptor
Spanish
:
Estolato de Eritromicina
Descriptor
Portuguese
:
Estolato de Eritromicina
Synonyms
English
:
Erythromycin Propionate Dodecyl Sulfate
Erythromycin Propionate Lauryl Sulfate
Tree Number:
D02.540.505.250.250
D04.345.349.250.250
D09.408.477.250.250
Definition
English
:
A macrolide antibiotic, produced by
Streptomyces
erythreus. It is the lauryl sulfate salt of the propionic ester of
erythromycin
. This
erythromycin
salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of
amino acids
during translation and assembly of
proteins.
Pharmacological Action:
Anti-Bacterial Agents
Enzyme Inhibitors
Gastrointestinal Agents
Protein Synthesis Inhibitors
History Note
English
:
91(75); was see under ERYTHROMYCIN 1975-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
28028
Unique Identifier:
D004918
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS