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ENDOTHELIN-3
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DeCS
Descriptor
English
:
Endothelin-3
Descriptor
Spanish
:
Endotelina-3
Descriptor
Portuguese
:
Endotelina-3
Tree Number:
D12.644.276.400.245
D12.776.467.400.245
D23.529.400.245
Definition
English
:
A 21-amino acid peptide that circulates in the
plasma
, but its source is not known.
Endothelin-3
has been found in high concentrations in the
brain
and may regulate important functions in
neurons
and
astrocytes
, such as proliferation and development. It also is found throughout the
gastrointestinal tract
and in the
lung
and
kidney
. (N Eng J Med 1995;333(6):356-63)
History Note
English
:
1997; use ENDOTHELINS 1991-1996; for BIG ENDOTHELIN 3 use ENDOTHELIN-3 (NM) 1993-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
33038
Unique Identifier:
D019334
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS