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CYCLIN-DEPENDENT KINASE INHIBITOR P57
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase Inhibitor p57
Descriptor
Spanish
:
Inhibidor p57 de las Quinasas Dependientes de la Ciclina
Descriptor
Portuguese
:
Inibidor de Quinase Dependente de Ciclina p57
Tree Number:
D12.644.360.225.700
D12.776.167.187.700
D12.776.476.225.700
D12.776.624.776.355.700
Definition
English
:
A potent inhibitor of
CYCLIN-DEPENDENT KINASES
in
G1 PHASE
and
S PHASE
. In
humans
, aberrant expression of p57 is associated with various
NEOPLASMS
as well as with
BECKWITH-WIEDEMANN SYNDROME.
Pharmacological Action:
Protein Kinase Inhibitors
History Note
English
:
2006(1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50933
Unique Identifier:
D050761
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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