Search on: COMPLEMENT C4B-BINDING PROTEIN 
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Descriptor English:   Complement C4b-Binding Protein 
Descriptor Spanish:   Proteína de Unión al Complemento C4b 
Descriptor Portuguese:   Proteína de Ligação ao Complemento C4b 
Tree Number:   D12.776.124.486.274.920.662
Definition English:   A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a). 
Pharmacological Action:   Complement Inactivating Agents
 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50837 
Unique Identifier:   D050716 

Occurrence in VHL:
 

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