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AUTOCRINE MOTILITY FACTOR
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DeCS
Descriptor
English
:
Autocrine Motility Factor
Descriptor
Spanish
:
Factor de Motilidad Autocrina
Descriptor
Portuguese
:
Fator Autócrino de Motilidade
Synonyms
English
:
Tumor Autocrine Motility Factor
Tree Number:
D08.811.399.475.200.174
D12.644.276.374.050
D12.776.467.374.050
D12.776.624.050
D23.101.840.100
D23.529.374.050
Definition
English
:
A protein cytokine secreted by tumor
cells
. It elicits increases in cell motility and phosphoinositide
metabolism
in the secreting cell via a pertussis toxin-sensitive G-protein
signal transduction
pathway. It is closely related to PHOSPHOHEXOSE ISOMERASE;
NEUROLEUKIN
; and maturation factor.
History Note
English
:
92; was TUMOR AUTOCRINE MOTILITY FACTOR (NM) 1987-91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30246
Unique Identifier:
D016554
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS